Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults Sobieraj, Diana M. Martinez, Brandon K. Hernández Vásquez, Akram Ross, Joseph S. Berg, Karina M. Steffens, David C. Baker, William L. 2019-08-08T21:16:50Z 2019-08-08T21:16:50Z 2019
dc.description.abstract OBJECTIVES To assess adverse effects of pharmacologic antidepressants for treatment of major depressive disorder (MDD) in adults 65 years of age or older. DESIGN Systematic review and meta‐analysis. SETTING Specialist or generalist outpatient setting, rehabilitation facility, and nursing facilities. PARTICIPANTS Persons 65 years and older with MDD. INTERVENTION Selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), bupropion, mirtazapine, trazodone, vilazodone, or vortioxetine compared with another antidepressant, placebo, or nonpharmacologic therapy. MEASUREMENTS Adverse events, arrhythmias, cognitive impairment, falls, fractures, hospitalization, mortality, QTc prolongation, serious adverse events, and withdrawals due to adverse events. es_ES
dc.description.peer-review Revisado por pares es_ES
dc.format application/pdf es_ES
dc.identifier.doi 10.1111/jgs.15966
dc.identifier.issn 0002-8614
dc.identifier.journal Journal of the American Geriatrics Society es_ES
dc.language.iso spa es_ES
dc.publisher Blackwell Publishing Inc. es_ES
dc.relation.ispartof Journal of the American Geriatrics Society
dc.rights info:eu-repo/semantics/embargoedAccess es_ES
dc.rights.uri es_ES
dc.source Universidad San Ignacio de Loyola es_ES
dc.source Repositorio Institucional - USIL es_ES
dc.subject Antidepressants es_ES
dc.subject Adverse events es_ES
dc.subject Older adults es_ES
dc.title Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults es_ES
dc.type info:eu-repo/semantics/article es_ES