Examinando por Autor "Pantoja-Torres, Betzi"
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- PublicaciónSólo datosAssociation between serum vitamin B12 levels and metabolic syndrome in a euthyroid population(Diabetes India, 2018-05) Guarnizo-Poma, Mirella; Urrunaga-Pastor, Diego; Montero-Suyo, Cory; Lazaro-Alcantara, Herbert; Paico-Palacios, Socorro; Pantoja-Torres, Betzi; Benites Zapata, Vicente A.Aims: To determine the association between serum levels of vitamin B12 and metabolic syndrome (MetS) in a population of euthyroid adults. Materials and methods: We carried out an analytical cross-sectional study in euthyroid adults of both sexes, who attended the outpatient service of a private clinic in Lima-Peru during the 2012–2016 period. Participants were divided into tertiles (low, intermediate and high) according to their serum vitamin B12 values. MetS was defined when three or more metabolic criteria were met by the participants. We elaborated crude and adjusted Poisson regression models to evaluate the association between the serum vitamin B12 tertiles and the presence of MetS. The reported association measure was the prevalence ratio (PR) with their respective 95% confidence intervals (95%CI).
- PublicaciónSólo datosHigh triglycerides to HDL-cholesterol ratio is associated with insulin resistance in normal-weight healthy adults(Elsevier B.V., 2019-02) Pantoja-Torres, Betzi; Toro Huamanchumo, Carlos J.; Urrunaga Pastor, Diego; Guarnizo Poma, Mirella; Lázaro Alcántara, Herbert; Paico Palacios, Socorro; Del Carmen Ranilla Seguin, Vitalia; Benites Zapata, Vicente A.Aim: To evaluate the association between high triglyceride/HDL-cholesterol (TG/HDL-C) ratio and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in normal-weight healthy adults. Methods: We carried out an analytical cross-sectional study in euthyroid non-diabetic adults, who attended the outpatient service of a private clinic in Lima-Peru from 2012 to 2016. Participants were divided in two groups according to the presence or absence of high TG/HDL-C ratio, IR or hyperinsulinemia after OGTT. TG/HDL-C ratio values ≥ 3 were considered as high. IR was defined as a Homeostasis Model Assessment (HOMA-IR) value ≥ 2.28 and hyperinsulinemia after OGTT as a serum insulin value ≥ 80μU/mL after 120 min of 75-g glucose intake. We elaborated crude and adjusted Poisson generalized linear models to evaluate the association between high TG/HDL-C ratio and IR or hyperinsulinemia after OGTT and reported the prevalence ratio (PR) with their respective 95% confidence intervals (95%CI). Results: We analyzed the data of 118 individuals. Prevalence of high TG/HDL-C ratio was 17.8% (n = 21) while the prevalence of IR and hyperinsulinemia after OGTT was 24.6% (n = 29) and 17.0% (n = 20), respectively. TG/HDL-C-ratio values were positively correlated with HOMA-IR (r = 0.498; p < 0.01) and serum insulin after OGTT (r = 0.326; p < 0.001). In the adjusted model, high TG/HDL-C ratio was associated with both IR (aPR = 3.16; 95%CI: 1.80–5.77) and hyperinsulinemia after OGTT (aPR = 2.36; 95%CI: 1.20–4.63). Conclusions: High TG/HDL-C ratio was associated with both IR markers used in our study, appearing to be a clinically useful tool to assess IR in euthyroid normal-weight adults without type 2 diabetes mellitus. © 2018 Diabetes India
- PublicaciónSólo datosHigh waist-to-hip ratio levels are associated with insulin resistance markers in normal-weight women(Elsevier Ltd, 2019-02) Benites Zapata, Vicente A.; Toro Huamanchumo, Carlos J.; Urrunaga-Pastor, Diego; Guarnizo-Poma, Mirella; Lázaro-Alcántara, Herbert; Paico-Palacios, Socorro; Pantoja-Torres, Betzi; Ranilla-Seguin, Vitalia Del CarmenAim: To assess the association between high waist-to-hip ratio (WHR) levels and insulin resistance (IR) or hyperinsulinemia after oral glucose tolerance test (OGTT) in a sample of normal-weight women. Methods: We conducted an analytical cross-sectional study in euthyroid non-diabetic women, who attended the outpatient service of a private clinic in Lima-Peru from 2012 to 2016. Participants were divided in two groups according to the presence or absence of high WHR levels, IR or hyperinsulinemia after OGTT. We considered WHR values > 0.85 as high levels. IR was defined as a Homeostasis Model Assessment (HOMA-IR) value > 2.39 and hyperinsulinemia after OGTT as a serum insulin value ≥ 80μU/mL after 120 min of 75-g glucose intake. We elaborated crude and adjusted Poisson generalized linear models to evaluate the association between high WHR levels and IR or hyperinsulinemia after OGTT and reported the prevalence ratio (PR) with their respective 95% confidence intervals (95%CI).